Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17792880 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL3969628 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL15251696 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL15251810 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL17789292 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL7264766 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL18775042 | 0.83 | CTSK (0.52) | ALDH1A1MEN1HTTKMT2ACA2 | |
| SCHEMBL28367643 | 0.83 | CTSK (0.52) | ALDH1A1MEN1HTTKMT2ACA2 | |
| SCHEMBL15308906 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MEN1HTTKMT2ASLC1A3 | |
| SCHEMBL15308918 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1HTTKMT2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| US-4645759-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0172347-A2 | Renin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-02-26 | — | — | EP | disclosed |