Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | LTA4H | P09960 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.69 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385705 | 0.95 | HRH3 (0.84) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL1385396 | 0.95 | HRH3 (0.84) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL7403863 | 0.93 | HRH3 (1.00) | HRH3MEN1LMNAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL7397299 | 0.92 | HRH3 (0.97) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL490523 | 0.92 | MEN1 (1.00) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL13698801 | 0.91 | LTA4H (0.87) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL1728918 | 0.91 | USP2 (0.78) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL3581930 | 0.91 | HRH3 (0.89) | HRH3KCNH2ACHERAD52HRH1 | |
| SCHEMBL5856197 | 0.90 | MEN1 (0.97) | HRH3MEN1LMNAHTTKMT2A | |
| SCHEMBL13698800 | 0.88 | USP2 (0.73) | HRH3MEN1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235290-A1 | RECOMBINANT CARDIOMYOCYTES AND CARDIOMYOCYTE CELL LINES EXPRESSING HERG | UNIV ALBERTA (CA) | 2023-07-27 | — | — | US | disclosed |
| WO-2001095902-A1 | A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS | RESPIRATORIUS AB (SE) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230235290-A1 | RECOMBINANT CARDIOMYOCYTES AND CARDIOMYOCYTE CELL LINES EXPRESSING HERG | TNNI3, MYLK2, TNNT2 | HRH3 3926/4885MEN1 3845/4885LMNA 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.