Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200463 | 0.85 | MAPT (0.70) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL5989854 | 0.84 | MAPT (0.72) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL5763109 | 0.83 | ENPP2 (0.58) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL13156273 | 0.81 | MAPT (0.75) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL28038606 | 0.79 | ALDH1A1 (0.67) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL7424178 | 0.79 | ALDH1A1 (0.57) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL5324355 | 0.78 | MAPT (0.63) | MAPTLMNAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL30198563 | 0.78 | MAPT (0.63) | MAPTLMNAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL1110499 | 0.78 | GAA (0.69) | MAPTLMNAMAPK1ALDH1A1HTT | |
| SCHEMBL3485338 | 0.78 | GAA (0.69) | MAPTLMNAMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |