Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434725 | 0.83 | LMNA (0.50) | MEN1MAPTKMT2AATMHPGD | |
| SCHEMBL1677509 | 0.80 | EPHX1 (0.41) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL7429306 | 0.80 | NAAA (0.47) | MAPTSMN1; SMN2EPHX1KDM4EEPHX2 | |
| SCHEMBL6380333 | 0.78 | KDM4E (0.43) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL25762505 | 0.77 | EPHX1 (0.40) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL15355129 | 0.76 | MEN1 (0.50) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL12581334 | 0.76 | MAOA (0.41) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL6018875 | 0.76 | ALDH1A1 (0.39) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL6018870 | 0.76 | ALDH1A1 (0.39) | MEN1MAPTKMT2AATMALDH1A1 | |
| SCHEMBL753960 | 0.75 | ALDH1A1 (0.46) | MEN1MAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |