Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119887 | 0.86 | LMNA (0.47) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL2117704 | 0.85 | KMT2A (0.49) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL8249383 | 0.83 | MAPT (0.43) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL22230701 | 0.83 | MAPT (0.43) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL10652250 | 0.83 | LMNA (0.61) | MAPTALDH1A1LMNANPSR1SLC6A3 | |
| SCHEMBL691016 | 0.83 | MAPT (0.46) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL5866532 | 0.82 | KMT2A (0.57) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL4370180 | 0.81 | MAPT (0.44) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL10275760 | 0.80 | GSK3B (0.53) | MAPTKMT2AALDH1A1MEN1SLC6A3 | |
| SCHEMBL28908332 | 0.80 | MAPT (0.41) | MAPTKMT2AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891899-A | Pharmaceutical xanthene compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |