Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 14/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434771 | 1.00 | UTS2R (0.38) | UTS2RSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7430561 | 0.89 | METAP2 (0.44) | UTS2RSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7430552 | 0.89 | METAP2 (0.44) | UTS2RSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7429954 | 0.89 | ALDH1A1 (0.37) | METAP2METAP1 | |
| SCHEMBL7429949 | 0.89 | ALDH1A1 (0.37) | METAP2METAP1 | |
| SCHEMBL7442580 | 0.83 | UTS2R (0.37) | UTS2RSLC6A2SLC6A4SLC6A3GABRB1 | |
| SCHEMBL7442591 | 0.83 | UTS2R (0.37) | UTS2RSLC6A2SLC6A4SLC6A3GABRB1 | |
| SCHEMBL7431633 | 0.81 | METAP2 (0.36) | UTS2RMETAP2METAP1 | |
| SCHEMBL7431641 | 0.81 | METAP2 (0.36) | UTS2RMETAP2METAP1 | |
| SCHEMBL7443773 | 0.81 | METAP2 (0.36) | UTS2RMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |