Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 13/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431633 | 1.00 | METAP2 (0.36) | METAP2METAP1GPR88UTS2RTACR3 | |
| SCHEMBL7431641 | 1.00 | METAP2 (0.36) | METAP2METAP1GPR88UTS2RTACR3 | |
| SCHEMBL7429954 | 0.92 | ALDH1A1 (0.37) | METAP2METAP1TACR3 | |
| SCHEMBL7442611 | 0.92 | ALDH1A1 (0.37) | METAP2METAP1TACR3 | |
| SCHEMBL7429949 | 0.92 | ALDH1A1 (0.37) | METAP2METAP1TACR3 | |
| SCHEMBL7440649 | 0.87 | TSHR (0.36) | — | |
| SCHEMBL7442501 | 0.86 | MEN1 (0.41) | — | |
| SCHEMBL7441757 | 0.84 | POLB (0.37) | GPR88 | |
| SCHEMBL7441749 | 0.84 | POLB (0.37) | GPR88 | |
| SCHEMBL7439032 | 0.82 | MMP2 (0.41) | METAP2METAP1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |