Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444797 | 0.83 | NAMPT (0.61) | NPC1RAB9AKMT2APOLBLMNA | |
| SCHEMBL7429214 | 0.82 | MEN1 (0.61) | NPC1RAB9AKMT2APOLBHPGD | |
| SCHEMBL6832529 | 0.80 | RAB9A (0.52) | NPC1RAB9AKMT2APOLBATM | |
| SCHEMBL10252948 | 0.80 | CNR2 (0.59) | CNR2NPC1RAB9AKMT2APOLB | |
| SCHEMBL26553954 | 0.79 | POLB (0.55) | CNR2NPC1RAB9AKMT2APOLB | |
| SCHEMBL7434740 | 0.79 | AVPR2 (0.53) | KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7438084 | 0.78 | NPC1 (0.71) | NPC1RAB9AKMT2APOLBLMNA | |
| Hydrochloric Acid SCHEMBL25402867 | 0.78 | POLB (0.57) | CNR2NPC1RAB9AKMT2APOLB | |
| SCHEMBL9466324 | 0.77 | RAB9A (0.63) | NPC1RAB9AKMT2APOLBSMN1; SMN2 | |
| SCHEMBL26553911 | 0.77 | SPHK1 (0.61) | CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |