Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279730 | 0.85 | MEN1 (0.61) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL7435890 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7437444 | 0.82 | KMT2A (0.64) | MEN1KMT2APOLBNPC1SMN1; SMN2 | |
| SCHEMBL7434832 | 0.82 | CNR2 (0.57) | KMT2APOLBNPC1RAB9AHPGD | |
| SCHEMBL7438908 | 0.81 | POLB (0.50) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL7431652 | 0.81 | MAPT (0.50) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7435728 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7426498 | 0.79 | ME2 (0.58) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7438927 | 0.79 | MEN1 (0.41) | MEN1KMT2APOLBRAB9AALDH1A1 | |
| SCHEMBL7434820 | 0.78 | ALDH1A1 (0.68) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |