Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8376612 | 0.97 | AVPR2 (0.51) | AVPR2OXTRAVPR1AMGLLHPGD | |
| Ethylene SCHEMBL8377847 | 0.88 | USP2 (0.51) | AVPR2OXTRAVPR1AMGLLHPGD | |
| SCHEMBL11193016 | 0.82 | SIGMAR1 (0.55) | AVPR2OXTRAVPR1AMGLLHPGD | |
| Ethylene SCHEMBL8379410 | 0.82 | SLC6A7 (0.51) | MGLLHPGDALDH1A1DRD2MEN1 | |
| SCHEMBL4376369 | 0.81 | DRD2 (0.66) | ALDH1A1DRD2MEN1KMT2APLA2G2A | |
| SCHEMBL7438028 | 0.81 | HPGD (0.76) | HPGDALDH1A1DRD2MEN1KMT2A | |
| SCHEMBL18978543 | 0.81 | ALDH1A1 (0.62) | AVPR2OXTRAVPR1AHPGDALDH1A1 | |
| SCHEMBL24120195 | 0.80 | HPGD (0.61) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12736237 | 0.79 | HSD17B10 (0.63) | AVPR2OXTRAVPR1AMGLLHPGD | |
| SCHEMBL7434832 | 0.79 | CNR2 (0.57) | HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |