Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612953 | 0.85 | SMN1; SMN2 (0.51) | CYP4F2CYP4A11 | |
| SCHEMBL1688815 | 0.84 | POLB (0.47) | POLBPTPN1 | |
| SCHEMBL16355781 | 0.82 | MAPT (0.43) | CYP4F2CYP4A11POLBCA1CA2 | |
| SCHEMBL6755422 | 0.81 | CYP17A1 (0.54) | IDO1EPHX2 | |
| SCHEMBL28250548 | 0.81 | LOXL2 (0.44) | POLBCA1CA2 | |
| SCHEMBL4615301 | 0.79 | NR1H4 (0.47) | FFAR1EPHX2POLBCA2 | |
| SCHEMBL10982252 | 0.79 | CYP4F2 (0.50) | FFAR1ADRB2ADRB1HRH3CYP4F2 | |
| SCHEMBL25262780 | 0.79 | CYP4F2 (0.60) | ADRB2ADRB1HRH3CYP4F2CYP4A11 | |
| SCHEMBL9135725 | 0.79 | MAPT (0.53) | FFAR1POLBCA1CA2 | |
| SCHEMBL14798407 | 0.79 | IDO1 (0.46) | IDO1EPHX2ADRB2ADRB1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |