Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 3/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 3/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688815 | 0.88 | POLB (0.47) | POLBMAPTTDP1FPR3FPR2 | |
| SCHEMBL16355781 | 0.86 | MAPT (0.43) | POLBMAPTTDP1CYP17A1CTNNB1 | |
| SCHEMBL5346268 | 0.83 | LOXL2 (0.53) | LOXL2POLBKLKB1PLGKLK1 | |
| SCHEMBL4615301 | 0.83 | NR1H4 (0.47) | POLBCA2 | |
| SCHEMBL4612953 | 0.83 | SMN1; SMN2 (0.51) | MAPT | |
| SCHEMBL1039226 | 0.82 | MAPT (0.47) | POLBMAPTTDP1CA1CA2 | |
| SCHEMBL8139519 | 0.81 | TPSAB1 (0.45) | LOXL2PLGNR1H2MAPTTDP1 | |
| SCHEMBL5807704 | 0.81 | POLB (0.42) | POLBMAPTTDP1FPR3FPR2 | |
| SCHEMBL8299387 | 0.81 | FPR2 (0.47) | POLBMAPTFPR3FPR2CA1 | |
| SCHEMBL9135786 | 0.81 | MAPT (0.52) | POLBMAPTTDP1FPR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623547-A | A kind of benzo/aphthofurans ketone aryl imine class compound and its synthetic method | 湖南大学 | 2018-10-09 | — | — | CN | claimed |
| CN-108623547-A | A kind of benzo/aphthofurans ketone aryl imine class compound and its synthetic method | 湖南大学 | 2018-10-09 | — | — | CN | disclosed |