Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444229 | 0.90 | CA2 (0.39) | CA2FFAR1KDM4EALDH1A1GAA | |
| SCHEMBL7439944 | 0.84 | KDM4E (0.35) | CA2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7438907 | 0.84 | CA2 (0.46) | CA2FFAR1KDM4EALDH1A1GAA | |
| SCHEMBL7439821 | 0.84 | CA2 (0.46) | CA2FFAR1 | |
| SCHEMBL7436351 | 0.82 | AHR (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL7429632 | 0.79 | KDM4E (0.31) | KDM4EALDH1A1GAA | |
| SCHEMBL7436205 | 0.78 | CA2 (0.46) | CA2FFAR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7440217 | 0.78 | CA2 (0.46) | CA2FFAR1KDM4EALDH1A1GAA | |
| SCHEMBL7445352 | 0.78 | CA2 (0.40) | CA2FFAR1KDM4EALDH1A1HPGD | |
| SCHEMBL11055545 | 0.78 | LMNA (0.50) | CA2KDM4EALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |