Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438907 | 0.83 | CA2 (0.46) | CA2MAPTLMNAFFAR1SMN1; SMN2 | |
| SCHEMBL7445352 | 0.83 | CA2 (0.40) | CA2MAPTLMNAFFAR1SMN1; SMN2 | |
| SCHEMBL11055550 | 0.80 | LMNA (0.50) | CA2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL11055545 | 0.80 | LMNA (0.50) | CA2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7434736 | 0.80 | LMNA (0.50) | CA2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL11279575 | 0.80 | LMNA (0.50) | CA2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7436820 | 0.80 | LMNA (0.45) | MAPTLMNAFFAR1SMN1; SMN2MEN1 | |
| SCHEMBL7432523 | 0.80 | KMT2A (0.35) | MAPTLMNASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7437035 | 0.80 | PNMT (0.38) | MAPTLMNAHTTFFAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7437739 | 0.79 | LMNA (0.49) | CA2MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |