Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441949 | 0.90 | CASP3 (0.42) | CASP3CASP1 | |
| SCHEMBL7437562 | 0.87 | CASP1 (0.55) | CASP3CASP1 | |
| SCHEMBL7427155 | 0.87 | CASP1 (0.54) | CASP1 | |
| SCHEMBL7447398 | 0.85 | CASP1 (0.53) | CASP1 | |
| SCHEMBL7675681 | 0.85 | CASP1 (0.53) | CASP3CASP1 | |
| SCHEMBL7438326 | 0.84 | CASP1 (0.50) | CASP1 | |
| SCHEMBL7434554 | 0.84 | CASP1 (0.52) | CASP1 | |
| SCHEMBL7679329 | 0.83 | CASP3 (0.47) | CASP3CASP1 | |
| SCHEMBL7427484 | 0.83 | CASP1 (0.47) | CASP1 | |
| SCHEMBL7444248 | 0.83 | CASP1 (0.47) | CASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | claimed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | claimed |
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |