Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 0.78 |
| ▸ | ITPR1 | Q14643 | 5/20 | 0.78 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.78 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.78 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.71 |
| ▸ | AKT1 | P31749 | 1/20 | 0.71 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437808 | 0.96 | ITPR3 (0.78) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL14094691 | 0.96 | ITPR3 (0.70) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4874594 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4871682 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL382820 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL10490812 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL98182 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL381458 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4321735 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL9382320 | 0.89 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5213975-A | — | — | None | — | — | JP | disclosed |
| EP-0520372-B1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5395828-A | Cardiovascular | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| JP-H05213975-A | INOSITOL PHOSPHATE ANALOG AS CALCIUM ANTAGONIST | HOECHST AG | 1993-08-24 | — | — | JP | disclosed |
| EP-0520372-A1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |