Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 0.78 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.78 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.78 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.78 |
| ▸ | AKT1 | P31749 | 1/20 | 0.78 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.71 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434973 | 0.96 | ITPR3 (0.78) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL14094691 | 0.96 | ITPR3 (0.70) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL382752 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9439795 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL29386031 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL282194 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL19532798 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9439431 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9387400 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL2905564 | 0.89 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520372-B1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5395828-A | Cardiovascular | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0520372-A1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |