Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432529 | 0.91 | PAX8 (0.52) | PAX8MEN1KMT2ALMNAHRH1 | |
| Water SCHEMBL7428725 | 0.90 | PAX8 (0.51) | PAX8MEN1KMT2ALMNAHRH1 | |
| SCHEMBL7442321 | 0.85 | PAX8 (0.51) | PAX8MEN1KMT2AHRH1DRD3 | |
| SCHEMBL10460775 | 0.85 | ABCB11 (0.57) | PAX8MEN1KMT2AHRH1DRD3 | |
| SCHEMBL7446953 | 0.84 | HRH1 (0.54) | PAX8MEN1HRH1DRD3KCNH2 | |
| SCHEMBL7446850 | 0.83 | PAX8 (0.51) | PAX8MEN1HRH1DRD3KCNH2 | |
| SCHEMBL7440209 | 0.83 | MEN1 (0.50) | PAX8MEN1KMT2AHRH1KCNH2 | |
| Oxalic Acid SCHEMBL7438851 | 0.82 | PAX8 (0.51) | PAX8MEN1KMT2ALMNAHRH1 | |
| SCHEMBL7438853 | 0.81 | MEN1 (0.49) | PAX8MEN1KMT2AHRH1HTR2A | |
| SCHEMBL7443328 | 0.81 | CACNA1B (0.42) | PAX8HRH1DRD3KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |