SCHEMBL7435010

SCHEMBL7435010

CN(CCCCCCO)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.71
MAOB P27338 3/20 0.58
MAOA P21397 1/20 0.58
CARM1 Q86X55 1/20 0.56
PRMT6 Q96LA8 1/20 0.56
PRMT8 Q9NR22 1/20 0.56
KDM4A O75164 2/20 0.56
KDM4C Q9H3R0 2/20 0.56
ACHE P22303 5/20 0.55
BCHE P06276 1/20 0.55
HTR7 P34969 2/20 0.54
APP P05067 1/20 0.52
TMEM97 Q5BJF2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10655267 1.00 SIGMAR1 (0.71) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL10925712 1.00 SIGMAR1 (0.71) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL4016132 1.00 SIGMAR1 (0.71) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL10650528 0.98 SIGMAR1 (0.68) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL5744436 0.92 SIGMAR1 (0.65) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL6028050 0.92 SIGMAR1 (0.61) SIGMAR1MAOBMAOACARM1PRMT6
Hydrochloric Acid SCHEMBL27998890 0.91 SIGMAR1 (0.62) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL7225346 0.90 SIGMAR1 (0.85) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL29733117 0.90 SIGMAR1 (0.85) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL16260101 0.85 SIGMAR1 (0.76) SIGMAR1MAOBMAOACARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662202-A1 PYRIDINE AND DIHYDROPYRIDINE COMPOUNDS AND USES THEREOF Clark Atlanta University, Inc. (US) 2025-12-17 EP disclosed
WO-2024167861-A1 PYRIDINE AND DIHYDROPYRIDINE COMPOUNDS AND USES THEREOF CLARK ATLANTA UNIVERSITY, INC. (US) 2024-08-15 WO disclosed
EP-0359547-B1 Pyridine compounds and pharmaceutical use thereof YOSHITOMI PHARMACEUTICAL (JP) 1996-01-24 EP disclosed
EP-0558094-A1 Pyridine compounds for treating amnesia YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1993-09-01 EP disclosed
US-5001137-A Pyridine compounds and pharmaceutical use thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-03-19 US disclosed
EP-0359547-A1 Pyridine compounds and pharmaceutical use thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-03-21 EP disclosed
EP-0289262-A2 Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1988-11-02 EP disclosed