SCHEMBL7435014 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	ITGB1	P05556	9/20	0.47

▸	ITGA4	P13612	9/20	0.47

▸	THRB	P10828	1/20	0.45

▸	L3MBTL1	Q9Y468	1/20	0.42

▸	NPSR1	Q6W5P4	1/20	0.42

▸	KMT2A	Q03164	1/20	0.42

▸	ALDH1A1	P00352	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7382557	0.95	ITGB1 (0.49)	ITGB1ITGA4THRBL3MBTL1NPSR1
SCHEMBL7390959	0.93	ITGB1 (0.44)	ITGB1ITGA4THRBNPSR1KMT2A
SCHEMBL7390925	0.90	ITGB1 (0.53)	ITGB1ITGA4THRBL3MBTL1NPSR1
SCHEMBL7484795	0.88	ITGB1 (0.45)	ITGB1ITGA4THRBL3MBTL1KMT2A
SCHEMBL7392261	0.88	THRB (0.47)	ITGB1ITGA4THRBL3MBTL1NPSR1
SCHEMBL7428230	0.86	ITGB1 (0.53)	ITGB1ITGA4KMT2AALDH1A1
SCHEMBL7425213	0.83	ITGB1 (0.49)	ITGB1ITGA4L3MBTL1KMT2AALDH1A1
SCHEMBL7388792	0.83	ITGB1 (0.46)	ITGB1ITGA4THRBL3MBTL1NPSR1
SCHEMBL7425047	0.83	ITGB1 (0.54)	ITGB1ITGA4L3MBTL1NPSR1KMT2A
SCHEMBL7426901	0.82	ITGA4 (0.55)	ITGB1ITGA4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999054321-A1	SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS	AVENTIS PHARMA LIMITED (GB)	1999-10-28	—	—	WO	disclosed