Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271150 | 0.86 | ERCC1 (0.54) | ERCC1ERCC4ALDH1A1LMNACA12 | |
| SCHEMBL6391038 | 0.86 | ALDH1A1 (0.67) | ERCC1ERCC4ALDH1A1LMNACA12 | |
| SCHEMBL7879611 | 0.85 | MEN1 (0.66) | ERCC1ERCC4ALDH1A1LMNACA12 | |
| SCHEMBL2550437 | 0.81 | ALDH1A1 (0.68) | ERCC1ERCC4ALDH1A1LMNACA12 | |
| SCHEMBL28145302 | 0.80 | EPHX2 (0.68) | EPHX2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL20932707 | 0.78 | ERCC1 (0.49) | ERCC1ERCC4ALDH1A1LMNACA12 | |
| SCHEMBL7934897 | 0.78 | EPHX2 (0.52) | ERCC1ERCC4ALDH1A1CA12CA1 | |
| SCHEMBL5315364 | 0.78 | EPHX2 (0.52) | ERCC1ERCC4ALDH1A1CA12CA1 | |
| SCHEMBL15630672 | 0.78 | EPHX2 (0.52) | ERCC1ERCC4ALDH1A1CA12CA1 | |
| SCHEMBL19049390 | 0.78 | LOXL2 (0.56) | ERCC1ERCC4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-A1 | Carboxylic-acid and sulphonic-acid amides | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | disclosed |