Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 6/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637025 | 0.92 | GNPAT (0.40) | CTSDGNPATCTSCENPEPNPSR1 | |
| Trifluoroacetic Acid SCHEMBL9614810 | 0.86 | ITGB1 (0.45) | ITGB1ITGA4PTPN1 | |
| Trifluoroacetic Acid SCHEMBL7432808 | 0.85 | GNPAT (0.47) | CTSDPTPN1GNPATENPEP | |
| SCHEMBL30880105 | 0.84 | ENPEP (0.45) | CTSDGNPATENPEP | |
| Trifluoroacetic Acid SCHEMBL4392857 | 0.83 | NPSR1 (0.38) | CTSDCTSCNPSR1 | |
| Trifluoroacetic Acid SCHEMBL7313048 | 0.82 | ITGB1 (0.43) | ITGB1ITGA4PTPN1 | |
| SCHEMBL30434998 | 0.82 | ECE1 (0.47) | CTSDCTSCNPSR1 | |
| SCHEMBL30792484 | 0.82 | PDCD1LG2 (0.43) | GNPATCTSCENPEPCA2CA4 | |
| SCHEMBL30695562 | 0.81 | CTSD (0.44) | CTSDGNPATCTSCENPEP | |
| SCHEMBL31031496 | 0.81 | CTSC (0.42) | CTSCENPEPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |