Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7435083 | 0.85 | ITGB1 (0.40) | GNPATCTSDENPEPPTPN1 | |
| SCHEMBL17732667 | 0.79 | GNPAT (0.56) | GNPATACECASP3CTSDMME | |
| Trifluoroacetic Acid SCHEMBL9614810 | 0.79 | ITGB1 (0.45) | ALDH1A1THRBALOX15NFKB1RECQL | |
| SCHEMBL6558875 | 0.79 | CASP1 (0.42) | GNPATCASP1CASP3CASP2CTSD | |
| SCHEMBL31162635 | 0.78 | GNPAT (0.51) | GNPATALDH1A1ACECASP1CASP3 | |
| SCHEMBL10442410 | 0.78 | ALDH1A1 (0.42) | GNPATALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL30799711 | 0.78 | ENPEP (0.50) | GNPATALDH1A1ENPEPPTPN1 | |
| SCHEMBL29695567 | 0.78 | GNPAT (0.47) | GNPATALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL29874685 | 0.77 | MME (0.40) | GNPATALDH1A1SMN1; SMN2CASP1CASP3 | |
| SCHEMBL30683407 | 0.76 | ENPEP (0.45) | GNPATCTSDMMEENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |