Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CTSS | P25774 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430937 | 0.87 | TRPM8 (0.61) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL6350990 | 0.87 | TRPM8 (0.61) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL7414480 | 0.87 | TRPM8 (0.61) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL7418088 | 0.87 | TRPM8 (0.61) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL7245549 | 0.87 | TRPM8 (0.61) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL7438373 | 0.86 | TRPM8 (0.49) | CTSBCTSSCTSLTRPM8CTRB1 | |
| SCHEMBL6282998 | 0.85 | CTSB (0.56) | CTSBCTSSCTSLCASP1F2 | |
| SCHEMBL11407932 | 0.85 | TRPM8 (0.56) | CTSBCTSSCTSLF2TRPM8 | |
| SCHEMBL11414657 | 0.85 | TRPM8 (0.56) | CTSBCTSSCTSLF2TRPM8 | |
| SCHEMBL11422143 | 0.84 | PPARA (0.56) | CTSBCTSSCTSLTRPM8CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |