Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391430 | 0.90 | FOLH1 (0.60) | FOLH1ALDH1A1ANPEPENPEP | |
| SCHEMBL7434454 | 0.89 | FOLH1 (0.59) | FOLH1ALDH1A1ANPEPENPEP | |
| SCHEMBL7427703 | 0.88 | FOLH1 (0.52) | FOLH1ALDH1A1 | |
| SCHEMBL7427744 | 0.85 | PPARA (0.48) | FOLH1PPARAALDH1A1ANPEPENPEP | |
| SCHEMBL7433519 | 0.85 | NPC1 (0.53) | FOLH1PPARAALDH1A1 | |
| SCHEMBL7431248 | 0.85 | FOLH1 (0.49) | FOLH1ALDH1A1ANPEPENPEP | |
| SCHEMBL7435388 | 0.84 | NPC1 (0.52) | FOLH1PPARAALDH1A1 | |
| SCHEMBL9587402 | 0.84 | FOLH1 (0.53) | FOLH1ALDH1A1ANPEPENPEP | |
| SCHEMBL7432902 | 0.83 | ALDH1A1 (0.46) | PPARAALDH1A1PTGER4 | |
| SCHEMBL27520404 | 0.83 | PPARA (0.53) | PPARAALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |