Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433519 | 0.99 | NPC1 (0.53) | NPC1RAB9AMITFSMN1; SMN2MEN1 | |
| SCHEMBL7435384 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2APOLBACE | |
| SCHEMBL7434454 | 0.87 | FOLH1 (0.59) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL7427703 | 0.86 | FOLH1 (0.52) | MEN1KMT2AALDH1A1FOLH1 | |
| SCHEMBL391430 | 0.86 | FOLH1 (0.60) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL7429797 | 0.85 | PPARA (0.48) | NPC1RAB9AMITFSMN1; SMN2MEN1 | |
| SCHEMBL7431596 | 0.84 | NPC1 (0.49) | NPC1RAB9AMITFSMN1; SMN2MEN1 | |
| SCHEMBL7435223 | 0.84 | FOLH1 (0.52) | PPARAALDH1A1FOLH1 | |
| SCHEMBL27537189 | 0.84 | RAB9A (0.56) | NPC1RAB9AMITFSMN1; SMN2MEN1 | |
| SCHEMBL7431248 | 0.83 | FOLH1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |