Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435223 | 0.85 | FOLH1 (0.52) | PPARAALDH1A1FOLH1ANPEPENPEP | |
| SCHEMBL7435916 | 0.84 | PPARA (0.45) | PPARAALDH1A1NPC1RAB9APTGDR | |
| SCHEMBL391430 | 0.80 | FOLH1 (0.60) | ALDH1A1FOLH1ANPEPENPEPNPC1 | |
| SCHEMBL7434454 | 0.79 | FOLH1 (0.59) | ALDH1A1FOLH1ANPEPENPEPNPC1 | |
| SCHEMBL7436909 | 0.78 | ALDH1A1 (0.46) | ALDH1A1FOLH1FNTAFNTBPGGT1B | |
| SCHEMBL7427703 | 0.76 | FOLH1 (0.52) | ALDH1A1FOLH1 | |
| SCHEMBL7426722 | 0.75 | ALDH1A1 (0.54) | ALDH1A1FOLH1FNTAFNTBPGGT1B | |
| SCHEMBL9587402 | 0.74 | FOLH1 (0.53) | ALDH1A1FOLH1ANPEPENPEPNPC1 | |
| SCHEMBL7433519 | 0.73 | NPC1 (0.53) | PPARAALDH1A1FOLH1NPC1RAB9A | |
| SCHEMBL7431248 | 0.73 | FOLH1 (0.49) | ALDH1A1FOLH1ANPEPENPEPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |