Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7443965 | 0.95 | ITGB3 (0.56) | ITGB3ITGA2BALOX15KDM4ELMNA | |
| SCHEMBL7435921 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BALOX15KDM4EF2 | |
| SCHEMBL7446782 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BALOX15KDM4EF2 | |
| Trifluoroacetic Acid SCHEMBL7448255 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BALOX15KDM4EF2 | |
| SCHEMBL7448790 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BALOX15KDM4EF2 | |
| Trifluoroacetic Acid SCHEMBL7444687 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BALOX15KDM4EF2 | |
| Trifluoroacetic Acid SCHEMBL7440547 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BALOX15KDM4EF2 | |
| SCHEMBL7445913 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BALOX15KDM4ELMNA | |
| SCHEMBL7443501 | 0.82 | LMNA (0.46) | ALOX15KDM4ELMNAALDH1A1CYP2C9 | |
| SCHEMBL7337939 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BALOX15KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | claimed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| WO-1992021673-A1 | NOVEL AZABICYCLOBENZISOQUINOLINES | SYNTEX (U.S.A.) INC. (US) | 1992-12-10 | — | — | WO | disclosed |