Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314052 | 0.92 | CHRM4 (0.42) | LMNAHRH1CCR3KCNH2KDM4E | |
| SCHEMBL7435280 | 0.82 | ITGB3 (0.61) | LMNAKDM4ECYP2C9CYP2C19MAPT | |
| SCHEMBL7443280 | 0.79 | MAOB (0.45) | LMNAHRH1CCR3KCNH2KDM4E | |
| Trifluoroacetic Acid SCHEMBL7443965 | 0.79 | ITGB3 (0.56) | LMNAKDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7435155 | 0.77 | CTSS (0.42) | KDM4ECYP2C9CYP2C19MAPTALDH1A1 | |
| SCHEMBL7435244 | 0.76 | NPY2R (0.52) | LMNAKDM4ECYP2C9CYP2C19CHRM4 | |
| SCHEMBL7337863 | 0.74 | KDM4E (0.46) | LMNAKDM4ECYP2C9CYP2C19MAPT | |
| SCHEMBL5800431 | 0.74 | KDM4E (0.61) | KDM4EL3MBTL1 | |
| SCHEMBL7444913 | 0.73 | ESR1 (0.46) | LMNAKDM4ECYP2C9CYP2C19CHRM4 | |
| SCHEMBL7435921 | 0.73 | ITGB3 (0.59) | KDM4ECYP2C9CYP2C19MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |