Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431596 | 0.99 | NPC1 (0.49) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7429796 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL392082 | 0.88 | ALDH1A1 (0.52) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7432011 | 0.88 | ALDH1A1 (0.45) | PPARASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7431904 | 0.88 | NR1H4 (0.48) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7432902 | 0.87 | ALDH1A1 (0.46) | PPARASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7431217 | 0.86 | KCNK3 (0.46) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7435388 | 0.85 | NPC1 (0.52) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7433519 | 0.84 | NPC1 (0.53) | PPARANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27537189 | 0.81 | RAB9A (0.56) | PPARANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |