Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327539 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| Pyrrocaine SCHEMBL25718 | 0.86 | MEN1 (0.70) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| SCHEMBL7431862 | 0.86 | TP53 (0.56) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| SCHEMBL7438110 | 0.85 | POLB (0.74) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| Pincainide SCHEMBL2110148 | 0.85 | MEN1 (0.73) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| SCHEMBL2096761 | 0.85 | MEN1 (0.73) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| SCHEMBL22407740 | 0.85 | MEN1 (0.73) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| Pyrrocaine SCHEMBL10757216 | 0.85 | MEN1 (0.68) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| SCHEMBL8556384 | 0.84 | MEN1 (0.60) | ALDH1A1MEN1KMT2AKCNH2ADRB1 | |
| Pyrrocaine SCHEMBL1651381 | 0.84 | MEN1 (0.67) | ALDH1A1MEN1KMT2AKCNH2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |