Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435500 | 0.85 | ALDH1A1 (0.57) | POLBMEN1KMT2AALOX15TSHR | |
| SCHEMBL7288776 | 0.82 | POLB (0.74) | POLBMEN1KMT2AALOX15TSHR | |
| SCHEMBL7437444 | 0.79 | KMT2A (0.64) | POLBMEN1KMT2ATSHRNPC1 | |
| SCHEMBL7431631 | 0.76 | ALDH1A1 (0.44) | POLBMEN1KMT2AALOX15RAB9A | |
| SCHEMBL7442119 | 0.75 | RAB9A (0.48) | POLBMEN1KMT2AALOX15RAB9A | |
| SCHEMBL7423903 | 0.75 | ALOX15 (0.60) | POLBMEN1KMT2AALOX15TSHR | |
| SCHEMBL25620144 | 0.75 | MEN1 (0.81) | POLBMEN1KMT2AALOX15RAB9A | |
| SCHEMBL7431085 | 0.74 | ALDH1A1 (0.55) | POLBMEN1KMT2ATSHRRAB9A | |
| SCHEMBL7434236 | 0.73 | KDM4E (0.63) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL18998184 | 0.73 | RAB9A (0.53) | MEN1KMT2ATSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |