Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162967 | 0.73 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL18010681 | 0.70 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL1376187 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL130616 | 0.64 | MAOA (0.35) | — | |
| SCHEMBL242542 | 0.64 | — | — | |
| SCHEMBL5189879 | 0.64 | — | — | |
| SCHEMBL29517242 | 0.64 | — | — | |
| SCHEMBL1162639 | 0.64 | — | — | |
| SCHEMBL29539 | 0.64 | — | — | |
| SCHEMBL8343541 | 0.62 | TRPA1 (0.34) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | claimed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | disclosed |