Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5641934 | 0.95 | EPHX1 (0.43) | ACEEPHX1ALOX5HPGDKMT2A | |
| Acetic Acid SCHEMBL9900974 | 0.84 | ACE (0.46) | ACEJAK2JAK1TYK2JAK3 | |
| Acetic Acid SCHEMBL9900145 | 0.82 | ACE (0.45) | ACEJAK2JAK1TYK2JAK3 | |
| Acetic Acid SCHEMBL9900147 | 0.80 | ACE (0.37) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL6274517 | 0.78 | ALOX15 (0.42) | ACEEPHX1JAK2JAK1TYK2 | |
| Acetic Acid Methyl Ester SCHEMBL2477680 | 0.78 | ALDH1A1 (0.42) | ACEJAK2JAK1TYK2JAK3 | |
| Acetonitrile SCHEMBL5397687 | 0.78 | ACE (0.36) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL27272482 | 0.78 | ACE (0.35) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL2672147 | 0.77 | ACE (0.35) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL21987659 | 0.77 | PLG (0.50) | ACEJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |