Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL19666277 | 0.98 | ACE (0.34) | ACEKDM4EJAK2JAK1TYK2 | |
| Acetic Acid SCHEMBL9900974 | 0.79 | ACE (0.46) | ACEJAK2JAK1TYK2JAK3 | |
| Acetic Acid SCHEMBL9900145 | 0.77 | ACE (0.45) | ACEJAK2JAK1TYK2JAK3 | |
| Ammonia Solution, Strong SCHEMBL7435862 | 0.77 | ACE (0.39) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL5641934 | 0.77 | EPHX1 (0.43) | ACE | |
| Acetic Acid SCHEMBL9900147 | 0.75 | ACE (0.37) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL766758 | 0.73 | PIK3CD (0.37) | ACEJAK2JAK1TYK2JAK3 | |
| Acetonitrile SCHEMBL5397687 | 0.73 | ACE (0.36) | ACEJAK2JAK1TYK2JAK3 | |
| SCHEMBL6274517 | 0.73 | ALOX15 (0.42) | ACEJAK2JAK1TYK2JAK3 | |
| Acetic Acid Methyl Ester SCHEMBL2477680 | 0.73 | ALDH1A1 (0.42) | ACEJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680946-B1 | Detection of cholinesterase inhibition with microfluidic devices and systems thereof | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2023-06-20 | — | — | US | disclosed |
| US-9877960-B2 | Learning and memory improver | SUNTORY HOLDINGS LIMITED (JP) | 2018-01-30 | — | — | US | disclosed |
| US-20150297584-A1 | LEARNING AND MEMORY IMPROVER | SUNTORY HOLDINGS LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | BCHE, ACHE, SMPD1 | ACE 224/4885KDM4E 779/4885JAK2 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.