Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.38 |
| ▸ | USP9X | Q93008 | 5/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435885 | 1.00 | CTSK (0.38) | CTSKUSP9XUCHL1USP5RIPK1 | |
| SCHEMBL7444352 | 1.00 | CTSK (0.38) | CTSKUSP9XUCHL1USP5RIPK1 | |
| SCHEMBL7439373 | 0.92 | ALDH1A1 (0.37) | CTSKRIPK1TACR3 | |
| SCHEMBL7430640 | 0.92 | ALDH1A1 (0.37) | CTSKRIPK1TACR3 | |
| SCHEMBL7434693 | 0.92 | ALDH1A1 (0.37) | CTSKRIPK1TACR3 | |
| SCHEMBL7446905 | 0.87 | TSHR (0.37) | CTSKCTSS | |
| SCHEMBL7446912 | 0.87 | TSHR (0.37) | CTSKCTSS | |
| SCHEMBL7437021 | 0.86 | CTSK (0.44) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL7447115 | 0.84 | HDAC1 (0.36) | CTSKCTSS | |
| SCHEMBL7447094 | 0.84 | HDAC1 (0.36) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |