Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447094 | 1.00 | HDAC1 (0.36) | HDAC1POLBALDH1A1KMT2ACTSK | |
| SCHEMBL7437021 | 0.90 | CTSK (0.44) | KMT2ACTSKMEN1CTSS | |
| SCHEMBL7446912 | 0.89 | TSHR (0.37) | ALDH1A1KMT2ACTSKMEN1PDE2A | |
| SCHEMBL7446905 | 0.89 | TSHR (0.37) | ALDH1A1KMT2ACTSKMEN1PDE2A | |
| SCHEMBL7439373 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CTSKPDE2A | |
| SCHEMBL7430640 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CTSKPDE2A | |
| SCHEMBL7434693 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CTSKPDE2A | |
| SCHEMBL7435893 | 0.84 | CTSK (0.38) | CTSKCTSS | |
| SCHEMBL7435885 | 0.84 | CTSK (0.38) | CTSKCTSS | |
| SCHEMBL7444352 | 0.84 | CTSK (0.38) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |