Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495730 | 0.93 | CA2 (0.36) | KDM4EMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL7439458 | 0.93 | MAPT (0.40) | KDM4ELTA4HSMN1; SMN2TSHRMAPT | |
| SCHEMBL7440244 | 0.92 | ADRB2 (0.38) | KDM4ELTA4HSMN1; SMN2TSHRMAPT | |
| SCHEMBL7434347 | 0.91 | MAPT (0.37) | LTA4HSMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL7443120 | 0.91 | LMNA (0.41) | KDM4ELTA4HSMN1; SMN2NPC1TSHR | |
| SCHEMBL7428130 | 0.91 | MAPT (0.37) | KDM4ELTA4HSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7446573 | 0.91 | AIMP2 (0.38) | KDM4ELTA4HSMN1; SMN2NPC1MAPT | |
| SCHEMBL7432813 | 0.89 | CA1 (0.42) | LTA4HSMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL7430176 | 0.89 | TEAD1 (0.44) | LTA4HSMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL7431674 | 0.89 | LMNA (0.42) | KDM4ESMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |