Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429208 | 0.89 | L3MBTL1 (0.52) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL7443335 | 0.87 | MAPT (0.53) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL7432590 | 0.86 | HTT (0.53) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL12453030 | 0.78 | NPSR1 (0.44) | MAPTHTTMEN1KMT2A | |
| SCHEMBL15876191 | 0.77 | LMNA (0.52) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL13938297 | 0.76 | HTT (0.65) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL13480435 | 0.76 | MAPT (0.65) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL15202883 | 0.75 | SYK (0.64) | MAPTL3MBTL1HTTSMN1; SMN2LMNA | |
| SCHEMBL12203721 | 0.75 | L3MBTL1 (0.49) | MAPTL3MBTL1HTTLMNAPOLB | |
| SCHEMBL15679441 | 0.75 | MAPT (0.64) | MAPTL3MBTL1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |