Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442659 | 1.00 | CACNA1C (0.41) | CACNA1CMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7432582 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1GAAKDM4EADRA2A | |
| SCHEMBL6653187 | 0.77 | ALDH1A1 (0.49) | ALDH1A1ADRA2APNMTADRA2BADRA2C | |
| SCHEMBL27693463 | 0.77 | MAPT (0.46) | CACNA1CMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16135451 | 0.77 | MAPT (0.46) | CACNA1CMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7511375 | 0.75 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2ADRA2APNMT | |
| SCHEMBL11030540 | 0.75 | ALDH1A1 (0.49) | CACNA1CMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15630433 | 0.75 | PNMT (0.55) | MAPTADRA2APNMTADRA2BADRA2C | |
| SCHEMBL11030539 | 0.75 | PNMT (0.62) | ADRA2APNMTADRA2BADRA2C | |
| SCHEMBL11725913 | 0.75 | PNMT (0.62) | ADRA2APNMTADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401676-B1 | Enzyme inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-01-11 | — | — | EP | disclosed |
| US-5212157-A | Tetrapeptides as inhibitors of HIV | BIO-MEGA, INC. (CA) | 1993-05-18 | — | — | US | disclosed |
| EP-0401676-A1 | Enzyme inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1990-12-12 | — | — | EP | disclosed |