Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120709 | 0.87 | MEN1 (0.48) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL8207399 | 0.85 | MEN1 (0.47) | MEN1KMT2ALMNAPOLBSIRT1 | |
| Malonic Acid SCHEMBL18092161 | 0.83 | KMT2A (0.40) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL5186156 | 0.80 | MEN1 (0.43) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL28375248 | 0.76 | MEN1 (0.40) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL7379470 | 0.75 | MEN1 (0.48) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL30236541 | 0.73 | TP53 (0.46) | MEN1KMT2ALMNAPOLBSIRT1 | |
| SCHEMBL9717102 | 0.72 | CA12 (0.43) | LMNAALDH1A1GAAMAPT | |
| SCHEMBL992746 | 0.72 | MAPT (0.45) | MEN1KMT2APOLBSIRT1MAPT | |
| SCHEMBL27883738 | 0.71 | MEN1 (0.49) | MEN1KMT2ALMNAPOLBSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137874-B2 | Organic graded spin on BARC compositions for high NA lithography | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-20 | — | — | US | disclosed |