SCHEMBL992746

SCHEMBL992746

O=C1CC(=O)OC(c2ccc(O)cc2)O1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
SIRT1 Q96EB6 1/20 0.45
APAF1 O14727 1/20 0.45
POLB P06746 1/20 0.45
ESR2 Q92731 11/20 0.42
ESR1 P03372 6/20 0.42
CYP19A1 P11511 3/20 0.40
CYP3A4 P08684 3/20 0.40
AKT1 P31749 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
YES1 P07947 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28525073 0.79 MAOB (0.40) MAPTCYP19A1MEN1KMT2A
SCHEMBL9244468 0.79 FADS1 (0.42) CYP19A1TDP1
SCHEMBL9164472 0.79 AKT1 (0.40) MAPTSIRT1POLBCYP19A1AKT1
SCHEMBL120709 0.78 MEN1 (0.48) MAPTSIRT1POLBCYP19A1ADORA3
SCHEMBL8207399 0.77 MEN1 (0.47) MAPTSIRT1POLBCYP19A1ADORA3
SCHEMBL28985350 0.75 ALDH1A1 (0.33) CYP3A4CA12HSD17B10
SCHEMBL3428777 0.75 LMNA (0.52) MAPTPOLBCYP19A1CYP3A4NPC1
SCHEMBL10590171 0.75 CYP19A1 (0.39) POLBCYP19A1MEN1KMT2AKDM4E
SCHEMBL6543433 0.73 HSD17B10 (0.45) MAPTSIRT1APAF1POLBESR2
SCHEMBL6175110 0.73 KMT2A (0.46) MAPTPOLBMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116390704-A Composition for whitening and/or lightening keratin materials 莱雅公司 2023-07-04 CN claimed
EP-1649901-B1 Light screening composition comprising a dibenzoylmethane derivative, a lipophilic amide and a compound capable of accepting energy from the excited triplet state of dibenzoylmethane; process for photostabilsation OREAL (FR) 2018-11-28 EP claimed
EP-2923690-A1 COMPOSITION FOR STABILISING PHOTOSENSITIVE COMPOUNDS Sensient Cosmetic Technologies (FR) 2015-09-30 EP claimed
EP-1649902-B1 Light screening composition comprising a dibenzoylmethane derivative, an arylalkyl benzoat derivative and a compound capable of accepting energie from the excited triplet state of dibenzoylmethane; process of photostabilisation OREAL (FR) 2012-07-11 EP claimed
EP-1649900-B1 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation OREAL (FR) 2012-04-18 EP claimed
US-20100254923-A1 COMPOSITION AND PROCESS FOR PROTECTING CELLULAR TARGETS FROM AGING AND PHOTODAMAGE L'ORÉAL (FR) 2010-10-07 US claimed
EP-1649900-A2 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation L'OREAL (FR) 2006-04-26 EP claimed
EP-1649902-A2 Light screening composition comprising a dibenzoylmethane derivative, an arylalkyl benzoat derivative and a compound capable of accepting energie from the excited triplet state of dibenzoylmethane; process of photostabilisation L'OREAL (FR) 2006-04-26 EP claimed
EP-1649901-A2 Light screening composition comprising a dibenzoylmethane derivative, a lipophilic amide and a compound capable of accepting energy from the excited triplet state of dibenzoylmethane; process for photostabilsation L'OREAL (FR) 2006-04-26 EP claimed
EP-3937896-B1 SUNSCREEN COMPOSITIONS COMPRISING BUTYL METHOXYDIBENZOYLMETHANE, TRIAZINE DERIVATIVES AND PHOTOSTABILIZER BASF SE (DE) 2025-01-15 EP disclosed
CN-119300802-A Personal care compositions for sensitive skin and methods of use thereof 高德美控股有限公司 2025-01-10 CN disclosed
CN-116390704-A Composition for whitening and/or lightening keratin materials 莱雅公司 2023-07-04 CN disclosed
CN-116390704-A Composition for whitening and/or lightening keratin materials 莱雅公司 2023-07-04 CN disclosed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US disclosed
US-6160124-A Method for treating or preventing arteriosclerosis JAPAN TOBACCO INC. (JP) 2000-12-12 US disclosed
US-6057343-A HAVE SUPERIOR HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIONS AND ARE USEFUL FOR THE TREATMENT OF DIABETES AND THE COMPLICATIONS THEREOF, AS WELL AS THERAPEUTIC AGENTS FOR RELATED DISEASES SUCH AS HYPERLIPIDEMIA JAPAN TOBACCO, INC. (JP) 2000-05-02 US disclosed
WO-2000022037-A1 SOLID, SHAPED AND COLORED WAX ARTICLES CLARIANT FINANCE (BVI) LIMITED (VG) 2000-04-20 WO disclosed
US-6037359-A ARTERIOSCLEROSIS PREVENTION; ANTIDIABETIC AGENTS; ANTILIPEMIC AND HYPOGLYCEMIC AGENTS JAPAN TOBACCO, INC. (JP) 2000-03-14 US disclosed
US-5939445-A ISOXAZOLIDINEDIONES COMPOUNDS AS HYPOGLYCEMIC AGENTS AND TREATMENT OF ARTERIOSCLEROSIS JAPAN TOBACCO, INC. (JP) 1999-08-17 US disclosed
US-5728720-A HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; TREATMENT OF DIABETES JAPAN TOBACCO INC. (JP) 1998-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254923-A1 COMPOSITION AND PROCESS FOR PROTECTING CELLULAR TARGETS FROM AGING AND PHOTODAMAGE RAD52, MMS19, XPA MAPT 1298/4885SIRT1 107/4885APAF1 1868/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 MAPT 168/4885SIRT1 254/4885APAF1 3401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.