Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483389 | 0.84 | NPC1 (0.51) | CA12CA1CA9ALDH1A1MAPT | |
| SCHEMBL31483452 | 0.84 | ALDH1A1 (0.52) | CA12CA1CA9ALDH1A1GAA | |
| SCHEMBL9685950 | 0.82 | LMNA (0.55) | ALDH1A1MAPTLMNAMAOAMAOB | |
| SCHEMBL8425372 | 0.78 | ALDH1A1 (0.43) | ALDH1A1RECQLMAPTLMNAPKM | |
| SCHEMBL8423212 | 0.77 | GSTP1 (0.46) | CA12CA1CA9ALDH1A1GAA | |
| SCHEMBL31483398 | 0.77 | BRD4 (0.42) | ALDH1A1MAPTLMNAMAOAMAOB | |
| SCHEMBL8421285 | 0.77 | ALDH1A1 (0.49) | CA12CA1CA9ALDH1A1GAA | |
| SCHEMBL8421512 | 0.76 | NPC1 (0.36) | ALDH1A1MAPTLMNAPKMMAOA | |
| SCHEMBL3428777 | 0.75 | LMNA (0.52) | ALDH1A1MAPTLMNAMAOAMAOB | |
| SCHEMBL992746 | 0.72 | MAPT (0.45) | CA12ESR1ESR2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162405-A | Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-11-10 | — | — | US | disclosed |