Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430086 | 0.74 | RNASEH1 (0.42) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL7438068 | 0.74 | KDM4E (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL7442188 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4EHTTDHODHHCAR3 | |
| SCHEMBL23877259 | 0.67 | MYC (0.44) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL7430168 | 0.67 | KDM4E (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL3948079 | 0.67 | DHODH (0.61) | KDM4ESMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL24986312 | 0.66 | GRIN2D (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL6274465 | 0.66 | MEN1 (0.40) | ALDH1A1KDM4ETP53CYP3A4L3MBTL1 | |
| SCHEMBL19919493 | 0.65 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19919492 | 0.64 | EIF4A3 (0.36) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435235-B1 | Isoquinoline derivatives and salts thereof as protease inhibitors. | SNOW BRAND MILK PRODUCTS CO LTD (JP) | 1995-03-08 | — | — | EP | claimed |