Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | TEC | P42680 | 2/20 | 0.38 |
| ▸ | BMX | P51813 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949484 | 0.78 | ALDH1A1 (0.46) | MEN1ALDH1A1TP53BLMKMT2A | |
| SCHEMBL27824102 | 0.72 | KDM4E (0.47) | MEN1ALDH1A1TP53BLMKMT2A | |
| SCHEMBL7433788 | 0.71 | KDM4E (0.54) | MEN1ALDH1A1TP53BLMKMT2A | |
| SCHEMBL30223610 | 0.69 | KDM4E (0.47) | MEN1ALDH1A1TP53KMT2AKDM4E | |
| SCHEMBL1564322 | 0.67 | CYP1A2 (0.53) | MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL7436231 | 0.66 | GRIN2D (0.41) | MEN1ALDH1A1TP53KMT2AL3MBTL1 | |
| SCHEMBL16409371 | 0.66 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AL3MBTL1KDM4E | |
| 1-Naphthol SCHEMBL356271 | 0.65 | CYP1A2 (0.77) | ALDH1A1KMT2AKDM4ECYP3A4CYP1A2 | |
| SCHEMBL31266689 | 0.65 | KDM4E (0.50) | MEN1ALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL28279288 | 0.65 | MAP2K3 (0.53) | ALDH1A1TP53KDM4ECYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121094-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES AS ANTI-HIV-AGENTS | PFIZER LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |