Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436249 | 0.80 | ACE (0.42) | ACE | |
| SCHEMBL7440962 | 0.74 | HSD11B1 (0.37) | MMEACE | |
| SCHEMBL7440453 | 0.68 | MME (0.44) | MMEACE | |
| SCHEMBL7437645 | 0.68 | ACE (0.41) | MMEACE | |
| SCHEMBL7425886 | 0.67 | HSD11B1 (0.44) | — | |
| SCHEMBL7438304 | 0.67 | ACE (0.40) | MMEACE | |
| SCHEMBL7432526 | 0.66 | HSD11B1 (0.46) | — | |
| SCHEMBL7428787 | 0.65 | KMT2A (0.45) | MMEACE | |
| SCHEMBL7439905 | 0.64 | MDM2 (0.36) | — | |
| SCHEMBL7434177 | 0.64 | HSD11B1 (0.38) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |