Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439905 | 0.84 | MDM2 (0.36) | ALDH1A1GAACYP2C9CYP2C19MDM2 | |
| SCHEMBL7435674 | 0.81 | CHRM1 (0.36) | ALDH1A1GAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7435783 | 0.76 | CPA3 (0.36) | ALDH1A1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL7436246 | 0.74 | MME (0.40) | ACEMME | |
| SCHEMBL7439919 | 0.73 | KMT2A (0.39) | ALDH1A1KMT2ATSHRACEMEN1 | |
| SCHEMBL7435682 | 0.71 | KMT2A (0.37) | ALDH1A1KMT2AACEMEN1 | |
| SCHEMBL7425886 | 0.70 | HSD11B1 (0.44) | HSD11B1ALDH1A1GAATP53CYP3A4 | |
| SCHEMBL7432526 | 0.69 | HSD11B1 (0.46) | HSD11B1ALDH1A1GAATP53CYP3A4 | |
| SCHEMBL7434177 | 0.67 | HSD11B1 (0.38) | HSD11B1ALDH1A1GAATSHRCHRM1 | |
| SCHEMBL7437844 | 0.66 | HSD11B1 (0.38) | HSD11B1ALDH1A1GAATSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |