Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438304 | 0.89 | ACE (0.40) | ACEMMEKMT2ACYP3A4CYP2C19 | |
| SCHEMBL7437652 | 0.80 | KMT2A (0.40) | ACETP53KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7440453 | 0.74 | MME (0.44) | ACEMME | |
| SCHEMBL7425886 | 0.73 | HSD11B1 (0.44) | TP53KMT2ACYP3A4CYP2C19MEN1 | |
| SCHEMBL7439232 | 0.73 | PLA2G10 (0.39) | — | |
| SCHEMBL7432526 | 0.72 | HSD11B1 (0.46) | TP53KMT2ACYP3A4CYP2C19MEN1 | |
| SCHEMBL7434177 | 0.70 | HSD11B1 (0.38) | ACEHSD11B1GAATSHRCHRM1 | |
| SCHEMBL7437844 | 0.69 | HSD11B1 (0.38) | HSD11B1GAATSHRCHRM1ALDH1A1 | |
| SCHEMBL7445423 | 0.69 | TSHR (0.41) | ACEKMT2AMEN1HSD11B1GAA | |
| SCHEMBL7443198 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |