SCHEMBL7436307

SCHEMBL7436307

N[C@H](Cc1ccccc1)[C@H](O)C(=O)NCC(=O)O

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.66
ANPEP P15144 1/20 0.66
RNPEP Q9H4A4 1/20 0.66
DNPEP Q9ULA0 1/20 0.66
MME P08473 5/20 0.57
ACE P12821 3/20 0.57
ALDH1A1 P00352 2/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57
HSD17B10 Q99714 1/20 0.57
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
ECE1 P42892 1/20 0.57
BLM P54132 1/20 0.57
NPEPPS P55786 1/20 0.57
KMT2A Q03164 1/20 0.57
SLC15A1 P46059 2/20 0.51
LTA4H P09960 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10774815 1.00 LAP3 (0.66) LAP3ANPEPRNPEPDNPEPMME
SCHEMBL7951029 0.86 LAP3 (0.68) LAP3ANPEPRNPEPDNPEPALDH1A1
SCHEMBL17097365 0.86 LAP3 (0.68) LAP3ANPEPRNPEPDNPEPALDH1A1
SCHEMBL20474481 0.84 LAP3 (0.70) LAP3ANPEPRNPEPDNPEPSLC15A1
Hydrochloric Acid SCHEMBL17595507 0.84 LAP3 (0.66) LAP3ANPEPRNPEPDNPEPALDH1A1
SCHEMBL5227811 0.84 LAP3 (0.70) LAP3ANPEPRNPEPDNPEPSLC15A1
SCHEMBL8494993 0.84 LAP3 (0.70) LAP3ANPEPRNPEPDNPEPSLC15A1
SCHEMBL28799521 0.83 LAP3 (0.64) LAP3ANPEPRNPEPDNPEPSLC15A1
SCHEMBL28799524 0.83 LAP3 (0.64) LAP3ANPEPRNPEPDNPEPSLC15A1
Hydrochloric Acid SCHEMBL20474460 0.83 LAP3 (0.68) LAP3ANPEPRNPEPDNPEPSLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4719231-A 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-01-12 US disclosed
US-4453003-A ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS UMEZAWA HAMAO (JP) 1984-06-05 US disclosed
US-4391986-A Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-07-05 US disclosed
US-4281180-A Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-07-28 US disclosed
US-4240975-A USED AS ENZYME INHIBITOR, ANTIFERTILITY AGENT, AND ENHANCES THE ANTITUMOR EFFECT OF BLEOMYCIN ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1980-12-23 US disclosed
US-4189604-A PEPTIDASE ENZYME INHIBITORS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1980-02-19 US disclosed