Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743134 | 0.84 | FLT3 (0.47) | FLT3EHMT2KMT2AMEN1NPC1 | |
| SCHEMBL741940 | 0.80 | SMYD3 (0.43) | FLT3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL740219 | 0.79 | FLT3 (0.48) | FLT3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL740522 | 0.77 | SMYD3 (0.48) | FLT3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL27520223 | 0.76 | SMYD3 (0.45) | FLT3SMYD3F7F3HRH4 | |
| SCHEMBL743889 | 0.76 | HRH4 (0.46) | FLT3SMYD3F7F3HRH4 | |
| SCHEMBL742366 | 0.75 | F7 (0.49) | FLT3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL739788 | 0.75 | SMYD3 (0.51) | FLT3KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL741656 | 0.75 | SMYD3 (0.44) | FLT3SMYD3F7F3HRH4 | |
| SCHEMBL27547475 | 0.75 | KMT2A (0.58) | FLT3KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |
| CN-1293057-C | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1438993-A | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2003-08-27 | — | — | CN | disclosed |